Ivermectin,CAS 70288-86-7
|
Product Name |
||||
|
Synonyms |
22,23-DIHYDROAVERMECTIN B1; 22,23-DIHYDROAVERMECTINE; CARDOMEC; EQVALEN; heartgard-30; IVERMECTIN; IVERMECTINE; IVOMEC; hyvermectin; mk-0933; mk933; IVERMECTIN HCL; Ivermectin EP2000; IVERMECTIN NOT LESS THAN 93.0% OF 22,23-DIHY- DROAVERMECTIN B1A, AND NOT LESS ; THAN 97.0% OF 22,23-DIHY-DROAVERMECTIN B1(B1A+B1B); IVERMECTIN EP(CRM STANDARD); IVERMECTIN USP(CRM STANDARD); IvermectineEp2000; IVERMECTINE(PATENT-NOSUPPLY); 22,23-Dihydro C-076B1; Ivosint |
|||
|
CAS |
||||
|
Molecular formula |
C48H74O14.C47H72O14 |
|||
|
Molecular Weight |
1736.16 |
|||
|
Molecular Structure |
 |
|||
|
Physical and Chemical Properties |
|
|||
|
General Description |
Off-White powder |
|||
|
Usage |
Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels. |
|||
|
Packing |
1KG/Bag or 25KG/Drum |
|||
|
Specifications |
||||
|
Items |
Standard |
|||
| Description | White crystalline powder | |||
| Identification | ||||
| Infra-red spectrum | Infra-red spectrum of the sample should correspond to that of the reference standard | |||
| High performance liquid chromatography | The chromatogram of the assay preparation exhibits major peaks for component H2B1a and component H2B1b,the retention times and sizes of which correspond to those exhibited in the chromatogram of the standard preparation | |||
| Appearance of Solution | The solution is clear and not more intensely coloured than reference solution BY7 | |||
| Solubility | Practically insoluble in water, freely soluble in methylene chloride, soluble in alcohol | |||
| Specific Rotation | -17°- -20° | |||
| Water | Less than 1.0% | |||
| Sulphated Ash | Not more than 0.1% | |||
| Heavy Metals | Not more than 20ppm | |||
| Residual Solvents:Limit of AlcoholLimit of FormamideLimit of MethanolLimit of Toluene | Less than 5.0%Less than 3.0%Not more than 3000ppmNot more than 890ppm | |||
| Related SubstancesImpurities at RRT 1.3 to 1.5Individual of all other impuritiesTotal | Not more than 2.5%Not more than 1%Not more than 5% | |||
| Bacterial Endotoxins | Less than 0.007EU/ug | |||
| ASSAYH2B1a+H2B1bH2B1a/ H2B1a+H2B1b | 95.0%-102.0%More than 90.0% | |||
