Oxytetracycline base
Product Name |
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Synonyms |
Oxytetracycline base; Oxytetracycline; (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione dihydrate; (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrate |
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CAS |
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Molecular formula |
C22H24N2O9.2(H2O) |
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Molecular Weight |
496.47 |
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Molecular Structure |
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Physical and Chemical Properties |
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General Description |
Yellow crystalline |
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Usage |
Broad-spectrum antibacterial effect on sensitive bacteria including pneumococcal, streptococcus, part of the grape bacteria, bacillus anthracis, tetanus bacillus, the pig pneumonia mycoplasma, chlamydia, helix, also has certain inhibitory effect. |
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Packing |
25kg/drum |
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Specifications |
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Items |
Standard |
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Appearance |
Yellow crystalline powder, very slightly soluble in water. It dissolves in dilute acid and alkaline solutions. |
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Identification |
a) TLC results |
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b) Color reaction with sulfuric acid |
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c) Color reaction with silver nitrate |
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Ph |
4.5 to 7.0 |
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Specific optical rotation |
-203°to -216° |
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Specific absorbance at 353nm |
290 to 310 |
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Light-absorbing impurities |
a) At 430nm not greater than 0.25 |
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b) At 490nm not greater than 0.20 |
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Related substances |
4-epioxytetracycline≤ 0.5% |
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Tetracycline hydrochloride≤2.0% |
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Peak on the tail of the main peak≤2.0% |
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Heavy metals |
Not more than 50ppm |
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Water |
6.0 % to 9.0% |
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Sulphated ash |
Not more than 0.5% |
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Assay |
95.0% -100.5%(C22H24N2O9) based onanhydrous substance |