Metronidazole benzoate CAS13182-89-3

Items

Specifications

Results

Appearance

White or slight yellowish,crystalline  powder or flakes

Slight yellowish crystalline powder

Identification：

Melting point(℃)

UV

IR

Reaction of primary aromatic amines

99～102

The solution shows an absorption maximum at 232nm and 275nm.The specific absorbtion at the 232nm is 525-575.

The sample spectrum complies with that of the reference standard spectrum.

The sample solution gives the reaction of primary aromatic amines.

99.4-99.5

Maximum absorption are 232nm and 275nm

Specific absorption is 544

Comforms

Comforms

Appearance of solution

The solution is not more opalescent than reference suspensions Ⅱ.

The solution is not more intensely coloured than reference solution GY3.

Comforms

Comforms

Acidity(ml)

≤0.25

0.07

Related Substances(HPLC)

Impurity A

Impurity B

Impurity C

Any other impurity %

Total Impurities %

≤0.1

≤0.1

≤0.1

≤0.1

≤0.2

N.D

N.D

N.D

0.5

0.7

Heavy metals(ppm)

≤20

Comforms

Loss on drying(%)

≤0.5

0.2

Sulphated ash(%)

≤0.1

0.05

Assay(calculated on the dried substance)%

98.5～101.0

100.1

Conclusion

This batch of metronidazole benzoate complies with the requirement of the specifications above.